Journal
CHEMICAL COMMUNICATIONS
Volume 53, Issue 49, Pages 6649-6652Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc03584e
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Funding
- Novartis MIT Center for Continuous Manufacturing
- National Science Foundation Graduate Research Fellowship Program [1122374]
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We report an automated flow chemistry platform that can efficiently perform a wide range of chemistries, including single/multi-phase and single/multi-step, with a reaction volume of just 14 mu L. The breadth of compatible chemistries is successfully demonstrated and the desired products are characterized, isolated, and collected online by preparative HPLC/MS/ELSD.
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