A Cost-Effectiveness Analysis of Intradiscal Electrothermal Therapy Compared with Circumferential Lumbar Fusion

Study DesignCost-effectiveness analysis. ObjectiveTo evaluate the cost-effectiveness of intradiscal electrothermal therapy (IDET) relative to circumferential lumbar fusion with femoral ring allograft (FRA) in the United Kingdom. Summary of Background DataCircumferential lumbar fusion is an established treatment for discogenic low back pain. However, IDET could be a cost-effective treatment alternative as it can be carried out as a day case. MethodsPatient-level data were available for patients with discogenic low back pain treated with FRA (n=37) in a randomized trial of FRA vs. titanium cage, and for patients recruited to a separate study evaluating the use of IDET (n=85). Both studies were carried out at a single institution in the United Kingdom. Patients were followed-up for 24months, with data collected on low back disability (Oswestry Disability Index), back and leg pain (visual analog scale), quality of life (Short Form 36), radiographic evaluations, and U.K. National Health Service (NHS) resource use. Cost-effectiveness was measured by the incremental cost per quality-adjusted life year (QALY) gained. ResultsBoth treatments produced statistically significant improvements in outcome at 24-month follow-up. NHS costs were significantly lower with IDET due to a shorter mean procedure time (377.4minutes vs. 49.9minutes) and length of stay (7days vs. 1.2days). At a threshold of 20,000 per QALY, the probability that IDET is cost effective is high. ConclusionsBoth treatments led to significant improvements in patient outcomes that were sustained for at least 24months. Costs were lower with IDET, and for appropriate patients IDET is an effective and cost-effective treatment alternative.