Journal
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
Volume -, Issue 10, Pages 1665-1668Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ejic.201500116
Keywords
Platinum; N-heterocyclic carbenes; Functionalization; Coordination chemistry
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Funding
- Centre National de la Recherche Scientifique (CNRS) (France)
- Ministere de l'Enseignement Superieur et de la Recherche (MESR)
- La Ligue contre le Cancer Region Grand Est
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We report oxime ligation in combination with metal ligand exchange as a novel orthogonal and practical approach to the multifunctionalization of NHC-platinum complexes. This strategy, which enables strong diversity enhancement of metallodrug candidates, could also be applied to selective bioconjugation.
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