Journal
CURRENT OPINION IN IMMUNOLOGY
Volume 45, Issue -, Pages 126-131Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.coi.2017.03.003
Keywords
-
Categories
Funding
- Ministry of Education, Culture, Sports, Science, and Technology in Japan
- Japan Sciences and Technology Agency, Core Research for Evolutional Science and Technology (CREST)
- Secom Science and Technology Foundation
- Grants-in-Aid for Scientific Research [16K15289] Funding Source: KAKEN
Ask authors/readers for more resources
Memory B cell generation and antibody production result from a differentiation process that begins when the surface BCR on naive B cells binds an antigen. How the choice between these fates is tempo-spatially regulated is still obscure, but recent advances have reinforced the concept that the combination of B cell-intrinsic heterogeneity and - extrinsic heterogeneity provided by cells such as T cells is a key determinant. As molecular regulators, the transcription factors IRF4 and Bach2, which participate in these fate choices, have been emerging.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available