4.7 Article

Targeted cancer imaging and photothermal therapy via monosaccharide-imprinted gold nanorods

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 50, Pages 6716-6719

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc02247f

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Funding

  1. National Science Fund for Distinguished Young Scholars [21425520]
  2. National Natural Science Foundation of China [21275073]
  3. Jiangsu Provincial Government [BRA2016351]
  4. State Key Laboratory of Analytical Chemistry for Life Science [5431ZZXM1605]

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Plasmonic nanomaterials have been widely used for photothermal therapy (PTT) of cancer, but their recognition specificity remains challenging. We prepared monosaccharide-imprinted gold nanorods (AuNRs) for targeted cancer PTT, using sialic acid (SA) as a representative monosaccharide. The SA-imprinted AuNRs exhibited good specificity, enabling the killing of cancer cells without damaging healthy cells.

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