Journal
DERMATOLOGIC CLINICS
Volume 35, Issue 3, Pages 291-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.det.2017.02.003
Keywords
Atopic dermatitis; Eczema; Atopic eczema; Epidemiology; Natural history; Clinical course
Categories
Funding
- NCATS NIH HHS [KL2 TR001870] Funding Source: Medline
- NIAMS NIH HHS [K24 AR051895] Funding Source: Medline
- Wellcome Trust [205039/Z/16/Z] Funding Source: Medline
- Wellcome Trust [205039/Z/16/Z] Funding Source: Wellcome Trust
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Atopic dermatitis (AD) is a chronic, relapsing condition, meaning that the intensity of symptoms usually fluctuates over time. Changes in skin physiology may be evident from birth, suggesting that AD may be a lifelong condition marked by intermittent symptoms/disease activity. Methodological considerations for studying the long-term course of AD are reviewed in detail. Improved measurement of the frequency and duration of active disease periods can help to elucidate more about the clinical course AD and the role of treatment in long-term outcomes.
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