Journal
NEUROSCIENCE BULLETIN
Volume 33, Issue 5, Pages 576-584Publisher
SPRINGER
DOI: 10.1007/s12264-017-0164-8
Keywords
Parkinson's disease; Rapid eye movement sleep behavior disorder; Risk factors; Parkinsonism
Categories
Funding
- National Natural Science Foundation of China [91649114]
- Jiangsu Provincial Special Program of Medical Science, China [BL2014042]
- Jiangsu Provincial Medical Key Discipline Project
- Suzhou Clinical Research Center of Neurological Disease [Szzx201503]
- Jiangsu Province Ordinary University Professional Degree Graduate Practice Innovation, China [SJZZ16-0242]
- Priority Academic Program Development of Jiangsu Higher Education Institutions, China
Ask authors/readers for more resources
Rapid eye movement sleep behavior disorder (RBD) is one of the most common non-motor symptoms of parkinsonism, and it may serve as a prodromal marker of neurodegenerative disease. The mechanism underlying RBD is unclear. Several prospective studies have reported that specific non-motor symptoms predict a conversion risk of developing a neurodegenerative disease, including olfactory dysfunction, abnormal color vision, autonomic dysfunction, excessive daytime sleepiness, depression, and cognitive impairment. Parkinson's disease (PD) with RBD exhibits clinical heterogeneity with respect to motor and non-motor symptoms compared with PD without RBD. In this review, we describe the main clinical and pathogenic features of RBD, focusing on its association with other non-motor symptoms of parkinsonism.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
