4.7 Editorial Material

A tetrad of chromatin interactions for chromosome pairing in X inactivation

Journal

NATURE STRUCTURAL & MOLECULAR BIOLOGY
Volume 24, Issue 8, Pages 607-608

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/nsmb.3447

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Funding

  1. Intramural NIH HHS [ZIA DK075033-10] Funding Source: Medline

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An unusual pairing of homologous X chromosomes occurs during X inactivation. A new study in mouse embryonic stem cells shows that telomeres and the telomeric RNA PAR-TERRA are responsible for additional pairwise interactions that guide Xic-Xic pairing.

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