4.4 Article

Retrospective investigation and evolutionary analysis of a novel porcine deltacoronavirus strain detected in Thailand from 2008 to 2015

Journal

ARCHIVES OF VIROLOGY
Volume 162, Issue 7, Pages 2103-2108

Publisher

SPRINGER WIEN
DOI: 10.1007/s00705-017-3331-3

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Funding

  1. National Research Council of Thailand [5080001]
  2. Agricultural Research Development Agency
  3. Chulalongkorn University
  4. Special Task Force for Activating Research (STAR), Swine Viral Evolution and Vaccine Research (SVEVR), Chulalongkorn University

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Porcine deltacoronavirus (PDCoV) in Thailand was first detected in 2015. We performed a retrospective investigation of the presence of PDCoV in intestinal samples collected from piglets with diarrhea in Thailand from 2008 to 2015 using RT-PCR. PDCoV was found to be present as early as February 2013. Phylogenetic analysis demonstrated that all PDCoV variants from Thailand differ from those from other countries and belong to a novel group of PDCoV that is separate from the US and Chinese PDCoV variants. Evolutionary analysis suggested that the Thai PDCoV isolates probably diverged from a different ancestor from that of the Chinese and US PDCoV isolates and that this separation occurred after 1994.

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