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How RNA acts as a nuclease: some mechanistic comparisons in the nucleolytic ribozymes

Journal

BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 45, Issue -, Pages 683-691

Publisher

PORTLAND PRESS LTD
DOI: 10.1042/BST20160158

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Funding

  1. Cancer Research UK

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Recent structural and mechanistic studies have shed considerable light on the catalytic mechanisms of nucleolytic ribozymes. The discovery of several new ribozymes in this class has now allowed comparisons to be made, and the beginnings of mechanistic groupings to emerge.

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