Journal
BLOOD
Volume 129, Issue 26, Pages 3403-3406Publisher
AMER SOC HEMATOLOGY
DOI: 10.1182/blood-2017-05-782292
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Funding
- Novartis
- Astellas
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Midostaurin was recently approved by the US Food and Drug Administration for the treatment of FLT3-mutant acute myeloid leukemia (AML). This is the first drug to receive regulatory approval for AML in the United States since the year 2000. Midostaurin is a small-molecule kinase inhibitor with activity against the receptor tyrosine kinase FLT3, and its approval will hopefully mark the beginning of an era of targeted agents for the treatment of molecularly defined subtypes of AML.
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