Journal
CURRENT PROBLEMS IN CANCER
Volume 41, Issue 3, Pages 194-200Publisher
MOSBY-ELSEVIER
DOI: 10.1016/j.currproblcancer.2017.01.002
Keywords
Genomic profiling; Adolescent and young adult cancer; Pediatric tumors; Whole-exome sequencing; RNA sequencing; Next-generation sequencing
Categories
Funding
- National Cancer Institute (NCI) [1U10CA180886]
Ask authors/readers for more resources
With the use of high-throughput molecular profiling technologies, precision medicine trials are ongoing for adults with cancer. Similarly, there is an interest in how these techniques can be applied to tumors in children and adolescents to expand our understanding of the biology of pediatric cancers and evaluate the clinical implications of genomic testing for these patients. This article reviews the early studies in pediatric oncology showing the feasibility of this approach, describe the future plans to evaluate the clinical implications in a multi-center clinical trial and identify the challenges of applying genomics in this patient population. Published by Elsevier Inc.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available