Journal
JOURNAL OF COSMETIC DERMATOLOGY
Volume 16, Issue 4, Pages E9-E14Publisher
WILEY
DOI: 10.1111/jocd.12315
Keywords
chemical peeling; collagen fibers; elastic fibers; microdermabrasion; salicylic acid peel
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BackgroundMicrodermabrasion and chemical peeling are popular, inexpensive, and safe methods for treatment of some skin disorders and to rejuvenate skin. ObjectivesTo study the alterations of the dermal connective tissue following salicylic acid peeling and microdermabrasion. MethodsTwenty patients were participated in our study. All participants underwent facial salicylic acid 30% peel or microdermabrasion (10 cases in each group) weekly for 6weeks. Punch biopsies were obtained from the clinically normal skin of the right postauricular region 1week before treatment (control group). Other punch skin biopsies were obtained 1week after the end of the treatments from the left postauricular area. This region was treated in a similar way to the adjacent lesional skin (treated group). We used routine histological techniques (H&E stain), special stains (Masson trichrome and orcein stains), and image analyzer to study the alterations of the dermal connective tissues. ResultsOur study demonstrates variations in the morphological changes between the control and the treated groups, and between chemical peels and microdermabrasion. Both salicylic acid 30% and microdermabrasion were associated with thickened epidermal layer, shallow dermal papillae, dense collagen, and elastic fibers. There was a significant increase among those treated sites vs control regarding epidermal thickness and collagen thickness. Also, there was a highly statistically significant increase among those treated with salicylic acid vs microdermabrasion regarding the epidermal, collagen, and elastin thickness. ConclusionsBoth methods stimulate the repair process. The mechanisms underlying these variations are open for further investigations.
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