4.7 Article

Survival after dementia diagnosis in five racial/ethnic groups

Journal

ALZHEIMERS & DEMENTIA
Volume 13, Issue 7, Pages 761-769

Publisher

WILEY
DOI: 10.1016/j.jalz.2016.12.008

Keywords

Dementia; Survival; Mortality; Race; Ethnicity; Disparities; Cohort; Epidemiology

Funding

  1. University of California, San Francisco
  2. Center for Aging in Diverse Communities under Resource Centers for Minority Aging Research program of the National Institute on Aging, National Institutes of Health [P30-AG15272]
  3. Kaiser Permanente Community Benefits Health Policy and Disparities Research Program, National Institute on Aging [K99AG053410, RF1A6052132, R01AG050782]
  4. National Institute of Neurological Disorders and Stroke of the National Institutes of Health [U54NS081760]

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Introduction: Information on anticipated survival time after dementia diagnosis among racially/ethnically diverse patients is needed to plan for care and evaluate disparities. Methods: Dementia-free health care members aged >= 64 years were followed (1/1/2000-12/31/2013) for dementia diagnosis and subsequent survival (n = 23,032 Asian American; n = 18,778 African American; n = 21,000 Latino; n = 4543 American Indian/Alaska Native; n = 206,490 white). Kaplan-Meier curves were estimated for survival after dementia diagnosis by race/ethnicity. We contrasted mortality patterns among people with versus without dementia using Cox proportional hazards models. Results: After dementia diagnosis (n = 59,494), whites had shortest median survival (3.1 years), followed by American Indian/Alaska Natives (3.4 years), African Americans (3.7 years), Latinos (4.1 years), and Asian Americans (4.4 years). Longer postdiagnosis survival among racial/ethnic minorities compared with whites persisted after adjustment for comorbidities. Racial/ethnic mortality inequalities among dementia patients mostly paralleled mortality inequalities among people without dementia. Discussion: Survival after dementia diagnosis differs by race/ethnicity, with shortest survival among whites and longest among Asian Americans. (C) 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.

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