Journal
ALZHEIMERS & DEMENTIA
Volume 13, Issue 7, Pages 761-769Publisher
WILEY
DOI: 10.1016/j.jalz.2016.12.008
Keywords
Dementia; Survival; Mortality; Race; Ethnicity; Disparities; Cohort; Epidemiology
Categories
Funding
- University of California, San Francisco
- Center for Aging in Diverse Communities under Resource Centers for Minority Aging Research program of the National Institute on Aging, National Institutes of Health [P30-AG15272]
- Kaiser Permanente Community Benefits Health Policy and Disparities Research Program, National Institute on Aging [K99AG053410, RF1A6052132, R01AG050782]
- National Institute of Neurological Disorders and Stroke of the National Institutes of Health [U54NS081760]
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Introduction: Information on anticipated survival time after dementia diagnosis among racially/ethnically diverse patients is needed to plan for care and evaluate disparities. Methods: Dementia-free health care members aged >= 64 years were followed (1/1/2000-12/31/2013) for dementia diagnosis and subsequent survival (n = 23,032 Asian American; n = 18,778 African American; n = 21,000 Latino; n = 4543 American Indian/Alaska Native; n = 206,490 white). Kaplan-Meier curves were estimated for survival after dementia diagnosis by race/ethnicity. We contrasted mortality patterns among people with versus without dementia using Cox proportional hazards models. Results: After dementia diagnosis (n = 59,494), whites had shortest median survival (3.1 years), followed by American Indian/Alaska Natives (3.4 years), African Americans (3.7 years), Latinos (4.1 years), and Asian Americans (4.4 years). Longer postdiagnosis survival among racial/ethnic minorities compared with whites persisted after adjustment for comorbidities. Racial/ethnic mortality inequalities among dementia patients mostly paralleled mortality inequalities among people without dementia. Discussion: Survival after dementia diagnosis differs by race/ethnicity, with shortest survival among whites and longest among Asian Americans. (C) 2017 the Alzheimer's Association. Published by Elsevier Inc. All rights reserved.
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