Journal
LUNG CANCER-TARGETS AND THERAPY
Volume 8, Issue -, Pages 31-38Publisher
DOVE MEDICAL PRESS LTD
DOI: 10.2147/LCTT.S104205
Keywords
breath sampling; volatile organic compounds; lung cancer; early detection; electronic nose
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Funding
- Tel Aviv University
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In lung cancer, the prognosis and treatment options depend directly on tumor size and its spread at the time of diagnosis. There is therefore a constant search for methods that will allow early detection of cancerous lung nodules. With advancing imaging technology and implantation of screening routines in high-risk populations by low-dose computerized tomography, a significant increase in the number of diagnosed small peripheral lesions can be expected. While early detection of small cancerous lesions carries the benefit of wider treatment options and better prognosis, the process of obtaining a biopsy to confirm a cancerous tissue is not free of complications and bears inconveniences and stress to the patient. This review discusses the potential use of exhaled breath analysis as a simple, noninvasive tool for early detection of lung cancer and characterization of suspicious lung nodules.
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