Journal
DERMATOLOGIC CLINICS
Volume 35, Issue 3, Pages 327-+Publisher
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.det.2017.02.005
Keywords
Atopic dermatitis; Eczema; Inflammation; T helper 2; Interleukin 4; Interleukin 13; Biologic
Categories
Ask authors/readers for more resources
Moderate to severe atopic dermatitis (AD) can be debilitating and often requires use of systemic immunosuppressant therapy to achieve adequate disease control. There are currently no US Food and Drug Administration-approved systemic agents for the long-term treatment of AD. Recent insight has identified the T helper 2 cytokines, interleukins 4 and 13, as playing a major role in the pathogenesis of AD. There are multiple novel biologic agents in development that target interleukins 4 and/or 13 for the treatment of moderate to severe AD. The age of targeted biologics for AD has arrived.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available