4.5 Article

Molecular characterization of Camelpox virus isolates from Bikaner, India: Evidence of its endemicity

Journal

ACTA TROPICA
Volume 171, Issue -, Pages 1-5

Publisher

ELSEVIER
DOI: 10.1016/j.actatropica.2017.03.011

Keywords

Camelpox; Isolation; PCR; Histopathology; Phylogenetic

Funding

  1. ICAR, New Delhi, India

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Camelpox is an important viral disease of camels, which may produce mild skin lesions or severe systemic infections. Camelpox virus (CMLV) isolates retrieved from an incidence of camelpox in camels at Bikaner, India were characterized on the basis of genotype and pathotype. Histopathological examination of the CMLV scab revealed intracytoplasmic-eosinophilic inclusion bodies. The phylogenetic analysis of all eight CMLV isolates for C18L gene nucleotide sequence revealed its clustering with its strains M-96 from Kazakhstan and CMS from Iran. The study will help to understand the transmission chain, pathobiology, and epidemiology of circulating CMLV strains. The full genome sequencing of some of the exemplary samples of CMLV is recommended in order to plan and implement a suitable control strategy. (C) 2017 Elsevier B.V. All rights reserved.

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