Journal
MATERIALS
Volume 10, Issue 5, Pages -Publisher
MDPI
DOI: 10.3390/ma10050507
Keywords
biofilm; dental materials; degradation; dental caries
Categories
Funding
- National Natural Science Foundation of China NSFC [81500879]
- Beijing Municipal Science and Technology [Z151100003915137]
- Beijing Municipal Administration of Hospitals' Youth [QML20161501]
- Beijing Municipal Administration of Hospitals Clinical Medicine Development of Special Funding Support [ZYLX201703]
- NIH [R01 DE17974]
- University of Maryland School of Dentistry
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Dental polymeric composites have become the first choice for cavity restorations due to their esthetics and capacity to be bonded to the tooth. However, the oral cavity is considered to be harsh environment for a polymeric material. Oral biofilms can degrade the polymeric components, thus compromising the marginal integrity and leading to the recurrence of caries. Recurrent caries around restorations has been reported as the main reason for restoration failure. The degradation of materials greatly compromises the clinical longevity. This review focuses on the degradation process of resin composites by oral biofilms, the mechanisms of degradation and its consequences. In addition, potential future developments in the area of resin-based dental biomaterials with an emphasis on anti-biofilm strategies are also reviewed.
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