Journal
CHEMICAL COMMUNICATIONS
Volume 53, Issue 57, Pages 8066-8069Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc03576d
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Funding
- National Key Scientific Program of China [21505039]
- Radboudumc PhD grant
- Institute of Chemical Immunology [024.002.009]
- Netherlands Organization for Scientific Research (NWO) Veni Grant [863.13.024]
- NWO Spinoza award
- ERC advanced grant PATHFINDER [269019]
- KWO of the Dutch Cancer Society [2009-4402]
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Insight into the behavior of individual immune cells, in particular cytokine secretion, will contribute to a more fundamental understanding of the immune system. In this work, we have developed a cell membrane-anchored sensor for the detection of cytokines secreted by single cells using a combination of aptamer-based sensors and droplet microfluidics.
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