Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 46, Issue -, Pages 46-53Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2017.01.006
Keywords
-
Categories
Funding
- JSPS [15K06959, 26251003, 15K14455, 15H05971]
- Grants-in-Aid for Scientific Research [15K14455, 15H05971, 26251003, 15K06959] Funding Source: KAKEN
Ask authors/readers for more resources
The assembly of rod-shaped chromosomes during mitosis is an essential prerequisite for faithful segregation of genetic information into daughter cells. Despite the long history of chromosome research, it is only recently that we have acquired powerful approaches and crucial tools that help to unlock the secret of this seemingly complex process. In particular, in vitro assays, mammalian genetics, Hi-C analyses and computer simulations have provided valuable information during the past two years. These studies are now beginning to elucidate how the core components of mitotic chromosomes, namely, histones, topoisomerase II alpha and condensins, cooperate with each other to convert very long stretches of DNA into rod-shaped chromosomes.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available