Journal
CHEMICAL COMMUNICATIONS
Volume 53, Issue 58, Pages 8231-8234Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc04789d
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- NHMRC CDF [APP1088966]
- University of Wollongong
- Griffith University
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This paper reports the development of a nonenzymatic, amplificationfree, and sensitive platform for the detection of microRNA based on a new class of electrocatalytically active superparamagnetic gold-loaded nanoporous iron oxide nanocubes (Au@NPFe2O3NC). The assay showed an excellent detection sensitivity down to 100 fM and specificity towards the analysis of miR-21 in cell lines and tissue samples derived from patients with oesophageal squamous-cell carcinoma (ESCC).
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