Journal
EMERGING INFECTIOUS DISEASES
Volume 23, Issue 8, Pages 1253-1259Publisher
CENTERS DISEASE CONTROL & PREVENTION
DOI: 10.3201/eid2308.170354
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Funding
- European Union's Horizon 2020 research and innovation program under Zika-PLAN [734584]
- MRC [MC_PC_15088] Funding Source: UKRI
- Medical Research Council [MC_PC_15088] Funding Source: researchfish
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We summarize the characteristics of dysphagia in 9 infants in Brazil with microcephaly caused by congenital Zika virus infection. The Schedule for Oral Motor Assessment, fiberoptic endoscopic evaluation of swallowing, and the videofluoroscopic swallowing study were used as noninstrumental and instrumental assessments. All infants had a degree of neurologic damage and showed abnormalities in the oral phase. Of the 9 infants, 8 lacked oral and upper respiratory tract sensitivity, leading to delays in initiation of the pharyngeal phase of swallowing. Those delays, combined with marked oral dysfunction, increased the risk for aspiration of food, particularly liquid foods. Dysphagia resulting from congenital Zika virus syndrome microcephaly can develop in infants > 3 months of age and is severe.
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