Journal
AMERICAN JOURNAL OF ROENTGENOLOGY
Volume 209, Issue 2, Pages 270-276Publisher
AMER ROENTGEN RAY SOC
DOI: 10.2214/AJR.17.18112
Keywords
FDG; glutamine; metabolism; molecular imaging; PET
Funding
- American Cancer Society Mentored Research Scholar grant [124443-MRSG-13-121-01-CDD]
- National Institutes of Health grant [1R01CA179072-01A1]
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OBJECTIVE. In this article, we provide a general overview of how cancer cells subvert critical metabolic pathways to support their growth and unchecked division. Furthermore, we outline how molecular imaging can diagnostically exploit the resulting differences between cancer and normal cells. CONCLUSION. Molecular PET can provide valuable information about the metabolic dysregulation in cancer.
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