Journal
BIOMEDICAL OPTICS EXPRESS
Volume 8, Issue 12, Pages 5560-5578Publisher
OPTICAL SOC AMER
DOI: 10.1364/BOE.8.005560
Keywords
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Funding
- European Unionapos
- s Horizon research and innovation program (Marie Sklodowska-Curie) [701859]
- Austrian Science Fund (FWF) [P26553-N20]
- Marie Curie Actions (MSCA) [701859] Funding Source: Marie Curie Actions (MSCA)
- Austrian Science Fund (FWF) [P26553] Funding Source: Austrian Science Fund (FWF)
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We introduce multi-directional optical coherence tomography (OCT), a technique for investigation of the scattering properties of directionally reflective tissue samples. By combining the concepts of multi-channel and directional OCT, this approach enables simultaneous acquisition of multiple reflectivity depth-scans probing a mutual sample location from differing angular orientations. The application of multi-directional OCT in retinal imaging allows for in-depth investigations on the directional reflectivity of the retinal nerve fiber layer, Henle's fiber layer and the photoreceptor layer. Major ophthalmic diseases (such as glaucoma or age-related macular degeneration) have been reported to alter the directional reflectivity properties of these retinal layers. Hence, the concept of multi-directional OCT might help to gain improved understanding of pathology development and progression. As a first step, we demonstrate the capabilities of multi-directional OCT in the eyes of healthy human volunteers. Published by The Optical Society under the terms of the Creative Commons Attribution 4.0 license.
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