Journal
ACS NANO
Volume 11, Issue 8, Pages 8273-8281Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acsnano.7b03369
Keywords
dual plasmonic; supraparticles; core@shell; self-assembly; multimodal imaging; tumor therapy
Categories
Funding
- National Natural Science Foundation of China [21422501, 21505096, 81530057]
- Foundation for Innovation Team of Bioanalytical Chemistry
- National Key Research Program of China [2016YFC0101200]
- Postdoctoral Science Foundation of China [2015M571796, 2015T80575]
- MOE Tier1 [RG107/15, RG2/16]
Ask authors/readers for more resources
We herein report aqueous fabrication of well-defined Au@ Cu2-xE (E = S, Se) core@shell dual plasmonic supraparticles (SPs) for multimodal imaging and tumor therapy at the in vivo level. By means of a modified self-limiting self-assembly based strategy, monodisperse core shell dual plasmonic SPs, including spherical Au@Cu2-xS SPs, Au@ Cu2-xSe SPs, and rod-like Au@Cu2-xS SPs, are reliably and eco-friendly fabricated in aqueous solution. Due to plasmonic coupling from the core and shell materials, the as-prepared hybrid products possess an extremely large extinction coefficient (9.32 L g(-1) cm(-1) for spherical AupCu(2-x)S SPs) at 808 nm, which endows their excellent photothermal effect. Furthermore, the hybrid core@shell SPs possess the properties of good biocompatibility, low nonspecific interactions, and high photothermal stability. So, they show favorable performances for photoacoustic imaging and X-ray computed tomography imaging as well as photothermal therapy of tumors, indicating their application potentials in biological field.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available