Journal
ELECTROCHEMISTRY COMMUNICATIONS
Volume 81, Issue -, Pages 5-9Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.elecom.2017.05.018
Keywords
Biomolecular recognition; Nanochannel array; Electrochemical detection; Thrombin
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Funding
- National Natural Science Foundation of China [21575163, 21635004]
- Natural Science Foundation of Jiangsu Province [BK20151437]
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A sensitive and label-free method of monitoring the thrombin-aptamer recognition reaction has been developed using an array of nanochannels coupled with an electrochemical detection technique. Due to the highly amplified ion current produced by an array of nanochannels compared to a single nanochannel/pore, a significant increase in detection sensitivity has been achieved.
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