Journal
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Volume 88, Issue 4, Pages 365-367Publisher
ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2017.05.004
Keywords
Extended-spectrum beta-lactamase; Multidrug resistance; KPC; Tetracycline; Resistant
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Funding
- Northeastern University Advanced Undergraduate Research Award
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We examined the in vitro activity of minocycline against 103 Klebsiella pneumoniae carbapenemase (KPC)producing Enterobacteriaceae isolates and found approximately half had susceptible (26%) or intermediate (26%) MICs. For a subset of 35 isolates, susceptibility was highest to tigecycline (71% FDA vs. 20% EUCAST) followed by minocycline (14%) and then doxycycline (6%). (C) 2017 Elsevier Inc. All rights reserved.
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