Journal
BIOCHEMISTRY
Volume 56, Issue 30, Pages 3863-3873Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acs.biochem.7b00536
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Funding
- National Institutes of Health [F32GM117816, GM-118176]
- National Science Foundation GRFP
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Advances in bioconjugation and native protein modification are appearing at a blistering pace, making it increasingly time consuming for practitioners to identify the best chemical method for modifying a specific amino acid residue in a complex setting. The purpose of this perspective is to provide an informative, graphically rich manual highlighting significant advances in the field over the past decade. This guide will help triage candidate methods for peptide alteration and will serve as a starting point for those seeking to solve long-standing challenges.
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