Journal
FUTURE SCIENCE OA
Volume 3, Issue 2, Pages -Publisher
FUTURE SCI LTD
DOI: 10.4155/fsoa-2016-0093
Keywords
antibiotics; antimicrobial activity; antimicrobial resistance; chemical diversity; medicinal chemistry; open-access drug discovery; organic chemistry; synthetic chemistry
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Funding
- Wellcome Trust Strategic Award [104797/Z/14/Z]
- Wellcome Trust [104797/Z/14/Z] Funding Source: Wellcome Trust
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The Community for Open Antimicrobial Drug Discovery (CO-ADD) is a not-for-profit, collaborative approach to discovering new antibiotics. We access novel chemical diversity from academic synthetic chemists, who collectively possess millions of untested compounds with chemical diversity that lie outside commercial collections. We perform high-throughput antimicrobial screening of pure compounds derived from both synthetic and natural sources free of charge. The resulting data can be used by participants for publication, patenting and development purposes, and is fed back into the research community through an open-access database after a 2-year period during which information is kept confidential to the provider. CO-ADD is fundamentally asking two questions: can the community work together to address the global threat of antimicrobial resistance; and are there as yet undiscovered, novel antimicrobial compounds already present within our diverse global chemistry community?
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