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Resistant Starch Regulates Gut Microbiota: Structure, Biochemistry and Cell Signalling

Journal

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
Volume 42, Issue 1, Pages 306-318

Publisher

KARGER
DOI: 10.1159/000477386

Keywords

Resistant starch; Gut microbiota; Nutrition

Funding

  1. National Key Research and Development Program of China [2016YFD0501201]
  2. Key Programs of Frontier Scientific Research of the Chinese Academy of Sciences [QYZDY-SSW-SMC008]
  3. Xiaoxiang Endowed University Professor Fund of Hunan Normal University [840140-008]

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Starch is one of the most popular nutritional sources for both human and animals. Due to the variation of its nutritional traits and biochemical specificities, starch has been classified into rapidly digestible, slowly digestible and resistant starch. Resistant starch has its own unique chemical structure, and various forms of resistant starch are commercially available. It has been found being a multiple-functional regulator for treating metabolic dysfunction. Different functions of resistant starch such as modulation of the gut microbiota, gut peptides, circulating growth factors, circulating inflammatory mediators have been characterized by animal studies and clinical trials. In this mini-review, recent remarkable progress in resistant starch on gut microbiota, particularly the effect of structure, biochemistry and cell signaling on nutrition has been summarized, with highlights on its regulatory effect on gut microbiota. (C) 2017 The Author(s) Published by S. Karger AG, Basel

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