Copper-Catalyzed Silylperoxidation Reaction of α,β-Unsaturated Ketones, Esters, Amides, and Conjugated Enynes

A synthetic method of copper-catalyzed silylperoxidation of alpha,beta-unsaturated carbonyl compounds and conjugated enynes has been developed. The realization of silylperoxidation of the carbon carbon double bond permits direct access to silicon-containing peroxy products in moderate to good yields. Furthermore, this protocol distinguishes itself by operational simplicity and exhibiting good tolerance of a wide scope of functional groups. This strategy provides an efficient approach to the 1,2-difunctionalization of alpha,beta-unsaturated carbonyl compounds and conjugated enynes.