Journal
ACS CATALYSIS
Volume 7, Issue 2, Pages 1392-1396Publisher
AMER CHEMICAL SOC
DOI: 10.1021/acscatal.6b03571
Keywords
copper catalysis; carbon dioxide; hydroboration; carboxylic acid; disubstituted alkenes
Categories
Funding
- Danish National Research Foundation [DNRF118]
- Aarhus University
Ask authors/readers for more resources
A protocol for the hydrocarboxylation of disubstituted alkenes and terminal alkynes providing access to different secondary carboxylic acids and malonic acid derivatives has been developed. This methodology relies on an initial hydroboration using 9-BBN followed by carboxylation with carbon dioxide in the presence of a copper catalyst and the additive, cesium fluoride. Different cyclohexene, styrene, and stilbene derivatives could be utilized, and alkynes could be transformed into their corresponding dicarboxylic acids in good yields. Finally, six different terpenoids were carboxylated using the developed procedure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available