4.8 Article

Spatial competition constrains resistance to targeted cancer therapy

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

How to Use a Chemotherapeutic Agent When Resistance to It Threatens the Patient

Elsa Hansen et al.

PLOS BIOLOGY (2017)

Review Oncology

Targeting CDK4 and CDK6: From Discovery to Therapy

Charles J. Sherr et al.

CANCER DISCOVERY (2016)

Article Biochemistry & Molecular Biology

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

Boyang Zhao et al.

Review Medicine, Research & Experimental

Targeting cancer with kinase inhibitors

Stefan Gross et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Review Pharmacology & Pharmacy

FDA-approved small-molecule kinase inhibitors

Peng Wu et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2015)

Article Oncology

The Model Muddle: In Search of Tumor Growth Laws

Philip Gerlee

CANCER RESEARCH (2013)

Article Biochemistry & Molecular Biology

The Proliferation-Quiescence Decision Is Controlled by a Bifurcation in CDK2 Activity at Mitotic Exit

Sabrina L. Spencer et al.

Article Oncology

Evolutionary Approaches to Prolong Progression-Free Survival in Breast Cancer

Ariosto S. Silva et al.

CANCER RESEARCH (2012)

Article Biochemistry & Molecular Biology

An Integrated Chemical Biology Approach Provides Insight into Cdk2 Functional Redundancy and Inhibitor Sensitivity

Aude Echalier et al.

CHEMISTRY & BIOLOGY (2012)

Article Multidisciplinary Sciences

Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors

Timothy R. Wilson et al.

NATURE (2012)

Article Multidisciplinary Sciences

Chemical-genetic analysis of cyclin dependent kinase 2 function reveals an important role in cellular transformation by multiple oncogenic pathways

Dai Horiuchi et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Multidisciplinary Sciences

Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration

M. Kasim Diril et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Article Biology

On measuring selection in experimental evolution

Luis-Miguel Chevin

BIOLOGY LETTERS (2011)

Article Oncology

Expression of p16 and Retinoblastoma Determines Response to CDK4/6 Inhibition in Ovarian Cancer

Gottfried E. Konecny et al.

CLINICAL CANCER RESEARCH (2011)

Review Oncology

The CDK inhibitors in cancer research and therapy

Jonas Cicenas et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2011)

Article Biochemistry & Molecular Biology

Switching Cdk2 On or Off with Small Molecules to Reveal Requirements in Human Cell Proliferation

Karl A. Merrick et al.

MOLECULAR CELL (2011)

Article Cell Biology

Cdk2 suppresses cellular senescence induced by the c-myc oncogene

Stefano Campaner et al.

NATURE CELL BIOLOGY (2010)

Article Multidisciplinary Sciences

Pattern of retinoblastoma pathway inactivation dictates response to CDK4/6 inhibition in GBM

W. Ruprecht Wiedemeyer et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)

Article Oncology

Adaptive Therapy

Robert A. Gatenby et al.

CANCER RESEARCH (2009)

Editorial Material Multidisciplinary Sciences

A change of strategy in the war on cancer

Robert A. Gatenby

NATURE (2009)

Article Biochemical Research Methods

Spheroid-based drug screen: considerations and practical approach

Juergen Friedrich et al.

NATURE PROTOCOLS (2009)

Article Biochemistry & Molecular Biology

Molecular basis of drug resistance in Aurora kinases

Fiona Girdler et al.

CHEMISTRY & BIOLOGY (2008)

Article Multidisciplinary Sciences

Cdk1 is sufficient to drive the mammalian cell cycle

David Santamaria et al.

NATURE (2007)

Article Biochemistry & Molecular Biology

Cdk2 knockout mice are viable

C Berthet et al.

CURRENT BIOLOGY (2003)

Article Oncology

Proliferation of cancer cells despite CDK2 inhibition

O Tetsu et al.

CANCER CELL (2003)

Review Oncology

The RB and p53 pathways in cancer

CJ Sherr et al.

CANCER CELL (2002)