Related references
Note: Only part of the references are listed.Physiological and therapeutic regulation of PCSK9 activity in cardiovascular disease
Simon Glerup et al.
BASIC RESEARCH IN CARDIOLOGY (2017)
A Century of Cholesterol and Coronaries: From Plaques to Genes to Statins
Joseph L. Goldstein et al.
CELL (2015)
New class PCSK9 blockers stride into cholesterol market
Cormac Sheridan
NATURE BIOTECHNOLOGY (2015)
Efficacy and Safety of Alirocumab in Reducing Lipids and Cardiovascular Events
Jennifer G. Robinson et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Efficacy and Safety of Evolocumab in Reducing Lipids and Cardiovascular Events
Marc S. Sabatine et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Exome-wide association analysis reveals novel coding sequence variants associated with lipid traits in Chinese
Clara S. Tang et al.
NATURE COMMUNICATIONS (2015)
Statin Intolerance
Zahid Ahmad
AMERICAN JOURNAL OF CARDIOLOGY (2014)
Demystifying Heparan Sulfate-Protein Interactions
Ding Xu et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 83 (2014)
The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion
Camilla Gustafsen et al.
CELL METABOLISM (2014)
PCSK9: A Key Modulator of Cardiovascular Health
Nabil G. Seidah et al.
CIRCULATION RESEARCH (2014)
Serum Proprotein Convertase Subtilisin/Kexin Type 9 and Cell Surface Low-Density Lipoprotein Receptor: Evidence for a Reciprocal Regulation
Hagai Tavori et al.
CIRCULATION (2013)
Molecular Mediators for Raft-dependent Endocytosis of Syndecan-1, a Highly Conserved, Multifunctional Receptor
Keyang Chen et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Towards automated crystallographic structure refinement with phenix.refine
Pavel V. Afonine et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2012)
Rosuvastatin, Proprotein Convertase Subtilisin/Kexin Type 9 Concentrations, and LDL Cholesterol Response: the JUPITER Trial
Zuhier Awan et al.
CLINICAL CHEMISTRY (2012)
Heparan Sulfate Biosynthesis: Regulation and Variability
Johan Kreuger et al.
JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY (2012)
Proprotein Convertase Substilisin/Kexin Type 9 Antagonism Reduces Low-Density Lipoprotein Cholesterol in Statin-Treated Hypercholesterolemic Nonhuman Primates
Hong Liang et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Molecular Interaction Studies Using Microscale Thermophoresis
Moran Jerabek-Willemsen et al.
ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES (2011)
Rspo3 Binds Syndecan 4 and Induces Wnt/PCP Signaling via Clathrin-Mediated Endocytosis to Promote Morphogenesis
Bisei Ohkawara et al.
DEVELOPMENTAL CELL (2011)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
ScFv Antibody-induced Translocation of Cell-surface Heparan Sulfate Proteoglycan to Endocytic Vesicles EVIDENCE FOR HEPARAN SULFATE EPITOPE SPECIFICITY AND ROLE OF BOTH SYNDECAN AND GLYPICAN
Anders Wittrup et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Genetic and Metabolic Determinants of Plasma PCSK9 Levels
Susan G. Lakoski et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2009)
AutoDock4 and AutoDockTools4: Automated Docking with Selective Receptor Flexibility
Garrett M. Morris et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2009)
Function and distribution of circulating human PCSK9 expressed extrahepatically in transgenic mice
Yi Luo et al.
JOURNAL OF LIPID RESEARCH (2009)
Natural Cytotoxicity Receptors NKp30, NKp44 and NKp46 Bind to Different Heparan Sulfate/Heparin Sequences
Marie-Lyn Hecht et al.
JOURNAL OF PROTEOME RESEARCH (2009)
A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates
Joyce C. Y. Chan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Genetic variants in PCSK9 in the Japanese population: Rare genetic variants in PCSK9 might collectively contribute to plasma LDL cholesterol levels in the general population
Yasuko Miyake et al.
ATHEROSCLEROSIS (2008)
Role of the N- and C-terminal domains in binding of apolipoprotein E isoforms to heparan sulfate and dermatan sulfate: A surface plasmon resonance study
Yuko Yamauchi et al.
BIOCHEMISTRY (2008)
Altered heparan sulfate structure in mice with deleted NDST3 gene function
Srinivas R. Pallerla et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Plasma PCSK9 preferentially reduces liver LDL receptors in mice
Aldo Grefhorst et al.
JOURNAL OF LIPID RESEARCH (2008)
Transmembrane domains of the syndecan family of growth factor coreceptors display a hierarchy of homotypic and heterotypic interactions
Ian C. Dews et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Heparan sulfate proteoglycans provide a signal to Plasmodium sporozoites to stop migrating and productively invade host cells
Alida Coppi et al.
CELL HOST & MICROBE (2007)
Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation
Timothy S. Fisher et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
The cellular trafficking of the secretory proprotein convertase PCSK9 and its dependence on the LDLR
Nasha Nassoury et al.
TRAFFIC (2007)
Structural and biophysical studies of PCSK9 and its mutants linked to familial hypercholesterolemia
David Cunningham et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Microarrays of heparin oligosaccharides obtained by nitrous acid depolymerization of isolated heparin
Jose L. de Paz et al.
CHEMICAL COMMUNICATIONS (2006)
Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9
S Rashid et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Transgenic expression of mammalian heparanase uncovers physiological functions of heparan sulfate in tissue morphogenesis, vascularization, and feeding behavior
E Zcharia et al.
FASEB JOURNAL (2004)
Statins upregulate PCSK9, the gene encoding the proprotein convertase neural apoptosis-regulated convertase-1 implicated in familial hypercholesterolemia
G Dubuc et al.
ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY (2004)
Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate
H Barth et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Structure of β-antithrombin and the effect of glycosylation on antithrombin's heparin affinity and activity
AJ McCoy et al.
JOURNAL OF MOLECULAR BIOLOGY (2003)