4.8 Article

CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Functional Genomic Landscape of Human Breast Cancer Drivers, Vulnerabilities, and Resistance

Richard Marcotte et al.

Article Biochemistry & Molecular Biology

Targeting BRCA1 and BRCA2 Deficiencies with G-Quadruplex-Interacting Compounds

Jutta Zimmer et al.

MOLECULAR CELL (2016)

Article Genetics & Heredity

G-quadruplex structures mark human regulatory chromatin

Robert Hansel-Hertsch et al.

NATURE GENETICS (2016)

Article Multidisciplinary Sciences

Mammalian polymerase θ promotes alternative NHEJ and suppresses recombination

Pedro A. Mateos-Gomez et al.

NATURE (2015)

Article Biotechnology & Applied Microbiology

High-throughput sequencing of DNA G-quadruplex structures in the human genome

Vicki S. Chambers et al.

NATURE BIOTECHNOLOGY (2015)

Article Multidisciplinary Sciences

BRCA2 prevents R-loop accumulation and associates with TREX-2 mRNA export factor PCID2

Vaibhav Bhatia et al.

NATURE (2014)

Article Multidisciplinary Sciences

Elevated Levels of G-Quadruplex Formation in Human Stomach and Liver Cancer Tissues

Giulia Biffi et al.

PLOS ONE (2014)

Article Biochemistry & Molecular Biology

ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

Luis Ignacio Toledo et al.

Article Chemistry, Multidisciplinary

G-Quadruplex DNA as a Molecular Target for Induced Synthetic Lethality in Cancer Cells

Keith I. E. McLuckie et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2013)

Article Multidisciplinary Sciences

Pif1 family helicases suppress genome instability at G-quadruplex motifs

Katrin Paeschke et al.

NATURE (2013)

Article Biochemistry & Molecular Biology

Mutability and mutational spectrum of chromosome transmission fidelity genes

Peter C. Stirling et al.

CHROMOSOMA (2012)

Article Cell Biology

R-loop-mediated genome instability in mRNA cleavage and polyadenylation mutants

Peter C. Stirling et al.

GENES & DEVELOPMENT (2012)

Article Biochemistry & Molecular Biology

Small-molecule-induced DNA damage identifies alternative DNA structures in human genes

Raphael Rodriguez et al.

NATURE CHEMICAL BIOLOGY (2012)

Article Cell Biology

Epigeneitc silencing of ribosomal RNA genes by Mybbp1a

Bertrand Chin-Ming Tan et al.

JOURNAL OF BIOMEDICAL SCIENCE (2012)

Article Oncology

Anticancer Activity of CX-3543: A Direct Inhibitor of rRNA Biogenesis

Denis Drygin et al.

CANCER RESEARCH (2009)

Article Biochemical Research Methods

ChIP-seq: Using high-throughput sequencing to discover protein-DNA interactions

Dominic Schmidt et al.

METHODS (2009)

Review Mathematical & Computational Biology

Simultaneous inference in general parametric models

Torsten Hothorn et al.

BIOMETRICAL JOURNAL (2008)

Article Biochemistry & Molecular Biology

Replication blocking lesions present a unique substrate for homologous recombination

Jordan D. Ward et al.

EMBO JOURNAL (2007)

Article Biochemical Research Methods

The comet assay: a method to measure DNA damage in individual cells

Peggy L. Olive et al.

NATURE PROTOCOLS (2006)

Article Biochemistry & Molecular Biology

Highly prevalent putative quadruplex sequence motifs in human DNA

AK Todd et al.

NUCLEIC ACIDS RESEARCH (2005)

Article Biochemistry & Molecular Biology

Prevalence of quadruplexes in the human genome

JL Huppert et al.

NUCLEIC ACIDS RESEARCH (2005)

Review Biochemistry & Molecular Biology

The comet assay for DNA damage and repair - Principles, applications, and limitations

AR Collins

MOLECULAR BIOTECHNOLOGY (2004)

Article Cell Biology

53BP1 is required for class switch recombination

IM Ward et al.

JOURNAL OF CELL BIOLOGY (2004)

Article Biochemistry & Molecular Biology

Mus81-Eme1 and Rqh1 involvement in processing stalled and collapsed replication forks

CL Doe et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)

Article Biochemistry & Molecular Biology

Role of BRCA2 in control of the RAD51 recombination and DNA repair protein

AA Davies et al.

MOLECULAR CELL (2001)

Article Biochemical Research Methods

Determining mutation rates in bacterial populations

WA Rosche et al.

METHODS-A COMPANION TO METHODS IN ENZYMOLOGY (2000)