4.8 Article

In trans paired nicking triggers seamless genome editing without double-stranded DNA cutting

Related references

Note: Only part of the references are listed.
Review Cell Biology

Mechanisms and Consequences of Double-Strand DNA Break Formation in Chromatin

Wendy J. Cannan et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2016)

Article Multidisciplinary Sciences

Rationally engineered Cas9 nucleases with improved specificity

Ian M. Slaymaker et al.

SCIENCE (2016)

Review Hematology

The clinical applications of genome editing in HIV

Cathy X. Wang et al.

BLOOD (2016)

Review Biochemistry & Molecular Biology

Biology and Applications of CRISPR Systems: Harnessing Nature's Toolbox for Genome Engineering

Addison V. Wright et al.

Review Biotechnology & Applied Microbiology

Gene Insertion Into Genomic Safe Harbors for Human Gene Therapy

Eirini P. Papapetrou et al.

MOLECULAR THERAPY (2016)

Article Multidisciplinary Sciences

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration

Keiichiro Suzuki et al.

NATURE (2016)

Article Multidisciplinary Sciences

Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage

Alexis C. Komor et al.

NATURE (2016)

Article Multidisciplinary Sciences

High-fidelity CRISPR-Cas9 nucleases with no detectable genome-wide off-target effects

Benjamin P. Kleinstiver et al.

NATURE (2016)

Article Biotechnology & Applied Microbiology

Enhancing homology-directed genome editing by catalytically active and inactive CRISPR-Cas9 using asymmetric donor DNA

Christopher D. Richardson et al.

NATURE BIOTECHNOLOGY (2016)

Review Biochemical Research Methods

Creating and evaluating accurate CRISPR-Cas9 scalpels for genomic surgery

Mehmet Fatih Bolukbasi et al.

NATURE METHODS (2016)

Article Biochemistry & Molecular Biology

Knock-in of large reporter genes in human cells via CRISPR/Cas9-induced homology-dependent and independent DNA repair

Xiangjun He et al.

NUCLEIC ACIDS RESEARCH (2016)

Article Biochemistry & Molecular Biology

Probing the impact of chromatin conformation on genome editing tools

Xiaoyu Chen et al.

NUCLEIC ACIDS RESEARCH (2016)

Review Genetics & Heredity

The emerging role of viral vectors as vehicles for DMD gene editing

Ignazio Maggio et al.

GENOME MEDICINE (2016)

Article Biotechnology & Applied Microbiology

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

Takeshi Maruyama et al.

NATURE BIOTECHNOLOGY (2015)

Article Biotechnology & Applied Microbiology

Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells

Van Trung Chu et al.

NATURE BIOTECHNOLOGY (2015)

Review Biotechnology & Applied Microbiology

Genome editing at the crossroads of delivery, specificity, and fidelity

Ignazio Maggio et al.

TRENDS IN BIOTECHNOLOGY (2015)

Article Multidisciplinary Sciences

A Generic Strategy for CRISPR-Cas9-mediated gene tagging

Daniel H. Lackner et al.

NATURE COMMUNICATIONS (2015)

Article Genetics & Heredity

Pharmacological inhibition of DNA-PK stimulates Cas9-mediated genome editing

Francis Robert et al.

GENOME MEDICINE (2015)

Article Multidisciplinary Sciences

Saturation editing of genomic regions by multiplex homology-directed repair

Gregory M. Findlay et al.

NATURE (2014)

Article Biochemical Research Methods

Adenoviral vector DNA for accurate genome editing with engineered nucleases

Maarten Holkers et al.

NATURE METHODS (2014)

Article Multidisciplinary Sciences

Homology-directed repair of DNA nicks via pathways distinct from canonical double-strand break repair

Luther Davis et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

Review Cell Biology

Stem cells: balancing resistance and sensitivity to DNA damage

Julia C. Liu et al.

TRENDS IN CELL BIOLOGY (2014)

Article Biochemistry & Molecular Biology

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

F. Ann Ran et al.

Article Biotechnology & Applied Microbiology

Targeted Gene Addition in Human Epithelial Stem Cells by Zinc-finger Nuclease-mediated Homologous Recombination

Andrea Coluccio et al.

MOLECULAR THERAPY (2013)

Article Biotechnology & Applied Microbiology

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

Prashant Mali et al.

NATURE BIOTECHNOLOGY (2013)

Article Multidisciplinary Sciences

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali et al.

SCIENCE (2013)

Article Clinical Neurology

Evidence-Based Path to Newborn Screening for Duchenne Muscular Dystrophy

Jerry R. Mendell et al.

ANNALS OF NEUROLOGY (2012)

Article Biochemistry & Molecular Biology

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme

Jianbin Wang et al.

GENOME RESEARCH (2012)

Article Biochemistry & Molecular Biology

Concerted nicking of donor and chromosomal acceptor DNA promotes homology-directed gene targeting in human cells

Manuel A. F. V. Goncalves et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Biochemistry & Molecular Biology

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects

Cherie L. Ramirez et al.

NUCLEIC ACIDS RESEARCH (2012)

Article Biotechnology & Applied Microbiology

Lentiviral Vector Design and Imaging Approaches to Visualize the Early Stages of Cellular Reprogramming

Eva Warlich et al.

MOLECULAR THERAPY (2011)

Article Biotechnology & Applied Microbiology

Genetic engineering of human pluripotent cells using TALE nucleases

Dirk Hockemeyer et al.

NATURE BIOTECHNOLOGY (2011)

Article Biochemical Research Methods

High-frequency genome editing using ssDNA oligonucleotides with zinc-finger nucleases

Fuqiang Chen et al.

NATURE METHODS (2011)

Article Biochemistry & Molecular Biology

Single-strand nicks induce homologous recombination with less toxicity than double-strand breaks using an AAV vector template

Michael J. Metzger et al.

NUCLEIC ACIDS RESEARCH (2011)

Article Biochemistry & Molecular Biology

Stimulation of homology-directed gene targeting at an endogenous human locus by a nicking endonuclease

Gijsbert P. van Nierop et al.

NUCLEIC ACIDS RESEARCH (2009)

Article Multidisciplinary Sciences

Generation of a nicking enzyme that stimulates site-specific gene conversion from the I-AniI LAGLIDADG homing endonuclease

Audrey McConnell Smith et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)

Review Cell Biology

Mechanism and regulation of human non-homologous DNA end-joining

MR Lieber et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2003)