4.8 Article

Electron ptychographic microscopy for three-dimensional imaging

Journal

NATURE COMMUNICATIONS
Volume 8, Issue -, Pages -

Publisher

NATURE PUBLISHING GROUP
DOI: 10.1038/s41467-017-00150-1

Keywords

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Funding

  1. National Basic Research Program of China [2015CB654901]
  2. National Natural Science Foundation of China [11474147]
  3. Natural Science Foundation of Jiangsu Province [BK20151383]
  4. International Science & Technology Cooperation Program of China [2014DFE00200]
  5. Fundamental Research Funds for the Central Universities [021314380077]
  6. EPSRC [EP/F048009/1, EP/K032518/1, EP/M010708/1, EP/K040375/1]
  7. EU (ESTEEM2 (Enabling Science and Technology through European Electron Microscopy) of the European Commission
  8. Engineering and Physical Sciences Research Council [EP/M010708/1, EP/F048009/1] Funding Source: researchfish
  9. EPSRC [EP/F048009/1, EP/M010708/1] Funding Source: UKRI

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Knowing the three-dimensional structural information of materials at the nanometer scale is essential to understanding complex material properties. Electron tomography retrieves three-dimensional structural information using a tilt series of two-dimensional images. In this paper, we report an alternative combination of electron ptychography with the inverse multislice method. We demonstrate depth sectioning of a nanostructured material into slices with 0.34 nm lateral resolution and with a corresponding depth resolution of about 24-30 nm. This three-dimensional imaging method has potential applications for the three-dimensional structure determination of a range of objects, ranging from inorganic nanostructures to biological macromolecules.

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