Journal
ONCOLOGY LETTERS
Volume 13, Issue 3, Pages 1491-1498Publisher
SPANDIDOS PUBL LTD
DOI: 10.3892/ol.2017.5609
Keywords
breast cancer; biomarkers; prognosis; diagnosis; drug response
Categories
Funding
- Ministry of Education, Culture, Sports, Science and Technology, Japan [26461921, 25293289, 24659592, 50175634]
- Grants-in-Aid for Scientific Research [24659592, 26461921, 25293289] Funding Source: KAKEN
Ask authors/readers for more resources
Biomarkers that facilitate the prediction of breast cancer prognosis can improve the quality of life in patients during the long period of illness and treatment. Particularly in recent years, with the advent of a more exhaustive analysis of genetic information and gene products, the molecular mechanisms at play during breast cancer have gradually become clearer. In the present study, a systematic review of the literature between 2009 and 2014 was conducted by searching for the keywords 'breast cancer', 'biomarkers', 'diagnosis', 'prognosis' and 'drug response' to clarify the present state of knowledge regarding biomarkers. In the final analysis, 16 studies on biomarkers for the breast cancer prognosis were retrieved. From these, 7 biomarkers in 9 studies were found to be strongly reliable predictors of prognosis and a further 7 biomarkers in 7 studies were poorly reliable. The use of these prognostic biomarkers should increase the options available for treatment algorithms.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available