4.5 Editorial Material

Details matter: the role of genomic location and assay standardization in DNA methylation analyses

Journal

EPIGENOMICS
Volume 9, Issue 7, Pages 933-935

Publisher

FUTURE MEDICINE LTD
DOI: 10.2217/epi-2017-0053

Keywords

biomarkers; design; DNA methylation; epigenetics; genomic location; methodological challenges; normalization; quality; standardization

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Only when including quality and standardization at every level of DNA methylation analyses, will we be able to achieve the robustness to independently validate DNA methylation analyses and to compare multiple methylation studies in systematic reviews. This is the only way to more efficiently develop future DNA methylation based biomarkers.

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