Related references
Note: Only part of the references are listed.Targeting metastasis-initiating cells through the fatty acid receptor CD36
Gloria Pascual et al.
NATURE (2017)
Glutamine activates STAT3 to control cancer cell proliferation independently of glutamine metabolism
A. Cacace et al.
ONCOGENE (2017)
DHA blocks TPA-induced cell invasion by inhibiting MMP-9 expression via suppression of the PPAR-γ/NF-κB pathway in MCF-7 cells
Jin-Ki Hwang et al.
ONCOLOGY LETTERS (2017)
Hexokinase 2 promotes tumor growth and metastasis by regulating lactate production in pancreatic cancer
Marybeth Anderson et al.
ONCOTARGET (2017)
Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer
Barbara Chiavarina et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
Louise van der Weyden et al.
NATURE (2017)
Epigenomic reprogramming during pancreatic cancer progression links anabolic glucose metabolism to distant metastasis
Oliver G. McDonald et al.
NATURE GENETICS (2017)
Proline metabolism supports metastasis formation and could be inhibited to selectively target metastasizing cancer cells
Ilaria Elia et al.
NATURE COMMUNICATIONS (2017)
Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity
Xenia Geeraerts et al.
FRONTIERS IN IMMUNOLOGY (2017)
Differential Site-Based Expression of Pentose Phosphate Pathway-Related Proteins among Breast Cancer Metastases
Yoon Jin Cha et al.
DISEASE MARKERS (2017)
Emerging Biological Principles of Metastasis
Arthur W. Lambert et al.
CELL (2017)
Enhanced OXPHOS, glutaminolysis and β-oxidation constitute the metastatic phenotype of melanoma cells
Mariana F. Rodrigues et al.
BIOCHEMICAL JOURNAL (2016)
Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway
Valery L. Payen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Metabolism in cancer metastasis
Georg F. Weber
INTERNATIONAL JOURNAL OF CANCER (2016)
Tumor slice culture system to assess drug response of primary breast cancer
Kishan A. T. Naipal et al.
BMC CANCER (2016)
L-Arginine supplementation inhibits the growth of breast cancer by enhancing innate and adaptive immune responses mediated by suppression of MDSCs in vivo
Yu Cao et al.
BMC CANCER (2016)
Hexokinase 2 is a determinant of neuroblastoma metastasis
Liat Edry Botzer et al.
BRITISH JOURNAL OF CANCER (2016)
Inhibition of the Glycolytic Activator PFKFB3 in Endothelium Induces Tumor Vessel Normalization, Impairs Metastasis, and Improves Chemotherapy
Anna Rita Cantelmo et al.
CANCER CELL (2016)
L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity
Roger Geiger et al.
CELL (2016)
Environment Impacts the Metabolic Dependencies of Ras-Driven Non-Small Cell Lung Cancer
Shawn M. Davidson et al.
CELL METABOLISM (2016)
One-Carbon Metabolism in Prostate Cancer: The Role of Androgen Signaling
Joshua M. Corbin et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells
Oliver D. K. Maddocks et al.
MOLECULAR CELL (2016)
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition
Marco Sciacovelli et al.
NATURE (2016)
Arginine dependence of tumor cells: targeting a chink in cancer's armor
M. D. Patil et al.
ONCOGENE (2016)
Early and multiple origins of metastatic lineages within primary tumors
Zi-Ming Zhao et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Tissue-specific and convergent metabolic transformation of cancer correlates with metastatic potential and patient survival
Edoardo Gaude et al.
NATURE COMMUNICATIONS (2016)
Up-regulation of PKM2 promote malignancy and related to adverse prognostic risk factor in human gallbladder cancer
Wei Lu et al.
SCIENTIFIC REPORTS (2016)
Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis
Stefan Christen et al.
CELL REPORTS (2016)
Fatty Acid Oxidation-Driven Src Links Mitochondrial Energy Reprogramming and Oncogenic Properties in Triple-Negative Breast Cancer
Jun Hyoung Park et al.
CELL REPORTS (2016)
p53 in the DNA-Damage-Repair Process
Ashley B. Williams et al.
COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2016)
Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis
Marie-Julie Nokin et al.
ELIFE (2016)
T Cells and Cancer: How Metabolism Shapes Immunity
Barbara Molon et al.
FRONTIERS IN IMMUNOLOGY (2016)
In vivo cancer metabolism is defined by the nutrient microenvironment
Ilaria Elia et al.
TRANSLATIONAL CANCER RESEARCH (2016)
Fundamentals of cancer metabolism
Ralph J. DeBerardinis et al.
SCIENCE ADVANCES (2016)
Sarcosine Up-Regulates Expression of Genes Involved in Cell Cycle Progression of Metastatic Models of Prostate Cancer
Zbynek Heger et al.
PLOS ONE (2016)
Genetic alterations in fatty acid transport and metabolism genes are associated with metastatic progression and poor prognosis of human cancers
Aritro Nath et al.
SCIENTIFIC REPORTS (2016)
Raman Spectroscopic Analysis Reveals Abnormal Fatty Acid Composition in Tumor Micro- and Macroenvironments in Human Breast and Rat Mammary Cancer
Sixian You et al.
SCIENTIFIC REPORTS (2016)
Oncometabolite D-2-Hydroxyglurate Directly Induces Epithelial-Mesenchymal Transition and is Associated with Distant Metastasis in Colorectal Cancer
Hugh Colvin et al.
SCIENTIFIC REPORTS (2016)
The metabolic fate of acetate in cancer
Zachary T. Schug et al.
NATURE REVIEWS CANCER (2016)
Tracing the origin of disseminated tumor cells in breast cancer using single-cell sequencing
Jonas Demeulemeester et al.
GENOME BIOLOGY (2016)
Clinical significance of T cell metabolic reprogramming in cancer
Christoph Herbel et al.
CLINICAL AND TRANSLATIONAL MEDICINE (2016)
Metabolic control of signalling pathways and metabolic auto-regulation
Doriane Lorendeau et al.
BIOLOGY OF THE CELL (2015)
Mitochondrial Genetics Regulate Breast Cancer Tumorigenicity and Metastatic Potential
Kyle P. Feeley et al.
CANCER RESEARCH (2015)
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
Ping-Chih Ho et al.
CELL (2015)
Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
Chih-Hao Chang et al.
CELL (2015)
PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer
Fanny Dupuy et al.
CELL METABOLISM (2015)
Epigenetics and Metabolism
Samuel T. Keating et al.
CIRCULATION RESEARCH (2015)
Low expression of Bin1, along with high expression of IDO in tumor tissue and draining lymph nodes, are predictors of poor prognosis for esophageal squamous cell cancer patients
Yunlong Jia et al.
INTERNATIONAL JOURNAL OF CANCER (2015)
Knockdown of PKM2 Suppresses Tumor Growth and Invasion in Lung Adenocarcinoma
Hong Sun et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Glutamate dehydrogenase is a novel prognostic marker and predicts metastases in colorectal cancer patients
Gaojie Liu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2015)
Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA)
Bethany N. Hannafon et al.
MOLECULAR CANCER (2015)
PKM2 regulates neural invasion of and predicts poor prognosis for human hilar cholangiocarcinoma
Guanzhen Yu et al.
MOLECULAR CANCER (2015)
Defining the Metabolome: Size, Flux, and Regulation
Nicola Zamboni et al.
MOLECULAR CELL (2015)
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
Xiaofeng Zheng et al.
NATURE (2015)
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
Kari R. Fischer et al.
NATURE (2015)
Oxidative stress inhibits distant metastasis by human melanoma cells
Elena Piskounova et al.
NATURE (2015)
Breast-cancer-secreted miR-122 reprograms glucose metabolism in premetastatic niche to promote metastasis
Miranda Y. Fong et al.
NATURE CELL BIOLOGY (2015)
Genomic landscape of carcinogen-induced and genetically induced mouse skin squamous cell carcinoma
Dany Nassar et al.
NATURE MEDICINE (2015)
Mutant IDH is sufficient to initiate enchondromatosis in mice
Makoto Hirata et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
A case control study of sarcosine as an early prostate cancer detection biomarker
Donna P. Ankerst et al.
BMC UROLOGY (2015)
Metabolic Plasticity of Metastatic Breast Cancer Cells: Adaptation to Changes in the Microenvironment
Rui V. Simoes et al.
NEOPLASIA (2015)
Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells
Bryce W. Carey et al.
NATURE (2015)
Metabolic reprogramming during TGFβ1-induced epithelial-to-mesenchymal transition
L. Jiang et al.
ONCOGENE (2015)
Cancer Evolution: Mathematical Models and Computational Inference
Niko Beerenwinkel et al.
SYSTEMATIC BIOLOGY (2015)
Paving the way for therapeutic prevention of tumor metastasis with agents targeting mitochondrial superoxide
Paolo E. Porporato et al.
MOLECULAR & CELLULAR ONCOLOGY (2015)
The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity
Jacques C. Mbongue et al.
VACCINES (2015)
Assessing breast cancer cell lines as tumour models by comparison of mRNA expression profiles
Krista Marie Vincent et al.
BREAST CANCER RESEARCH (2015)
The combination of the expression of hexokinase 2 and pyruvate kinase M2 is a prognostic marker in patients with pancreatic cancer
Hisataka Ogawa et al.
MOLECULAR AND CLINICAL ONCOLOGY (2015)
Metastasis Suppressor KISS1 Seems to Reverse the Warburg Effect by Enhancing Mitochondrial Biogenesis
Wen Liu et al.
CANCER RESEARCH (2014)
Indoleamine 2,3-dioxygenase promotes peritoneal metastasis of ovarian cancer by inducing an immunosuppressive environment
Yuko Tanizaki et al.
CANCER SCIENCE (2014)
Methionine Metabolism Regulates Maintenance and Differentiation of Human Pluripotent Stem Cells
Nobuaki Shiraki et al.
CELL METABOLISM (2014)
Blocking Lipid Synthesis Overcomes Tumor Regrowth and Metastasis after Antiangiogenic Therapy Withdrawal
Nor Eddine Sounni et al.
CELL METABOLISM (2014)
In vitro models of the metastatic cascade: from local invasion to extravasation
S. Bersini et al.
DRUG DISCOVERY TODAY (2014)
Germline mutations in FH confer predisposition to malignant pheochromocytomas and paragangliomas
Luis Jaime Castro-Vega et al.
HUMAN MOLECULAR GENETICS (2014)
Implications of differences in expression of sarcosine metabolism-related proteins according to the molecular subtype of breast cancer
Ja Kyung Yoon et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2014)
Site-specific metabolic phenotypes in metastatic breast cancer
Hye Min Kim et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2014)
Quantitative flux analysis reveals folate-dependent NADPH production
Jing Fan et al.
NATURE (2014)
PGC-lα mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote metastasis
Valerie S. LeBleu et al.
NATURE CELL BIOLOGY (2014)
Molecular analysis of circulating tumour cells-biology and biomarkers
Matthew G. Krebs et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2014)
Mesenchymal Phenotype Predisposes Lung Cancer Cells to Impaired Proliferation and Redox Stress in Response to Glutaminase Inhibition
Danielle B. Ulanet et al.
PLOS ONE (2014)
Inverse hormesis of cancer growth mediated by narrow ranges of tumor-directed antibodies
Oliver M. T. Pearce et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Expression of Indoleamine 2,3-Dioxygenase and Infiltration of FOXP3+Regulatory T Cells Are Associated with Aggressive Features of Papillary Thyroid Microcarcinoma
Han Suk Ryu et al.
THYROID (2014)
Targeting EMT in cancer: opportunities for pharmacological intervention
Felicity M. Davis et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Identification and validation of dysregulated metabolic pathways in metastatic renal cell carcinoma
Nicole M. A. White et al.
TUMOR BIOLOGY (2014)
A Mitochondrial Switch Promotes Tumor Metastasis
Paolo E. Porporato et al.
CELL REPORTS (2014)
Core Needle Biopsy of Breast Cancer Tumors Increases Distant Metastases in a Mouse Model
Edward Gitau Mathenge et al.
NEOPLASIA (2014)
Cancer/stroma interplay via cyclooxygenase-2 and indoleamine 2,3-dioxygenase promotes breast cancer progression
Jing-Yi Chen et al.
BREAST CANCER RESEARCH (2014)
Microenvironmental Influences on Metastasis Suppressor Expression and Function during a Metastatic Cell's Journey
Wen Liu et al.
CANCER MICROENVIRONMENT (2014)
Risk of tumor cell seeding through biopsy and aspiration cytology
K. Shyamala et al.
JOURNAL OF INTERNATIONAL SOCIETY OF PREVENTIVE AND COMMUNITY DENTISTRY (2014)
Metabolomics for Biomarker Discovery in Gastroenterological Cancer
Shin Nishiumi et al.
METABOLITES (2014)
Succinate dehydrogenase inhibition leads to epithelial-mesenchymal transition and reprogrammed carbon metabolism
Paul-Joseph P. Aspuria et al.
CANCER & METABOLISM (2014)
Tumor Cell Dissemination: Emerging Biological Insights from Animal Models and Cancer Patients
Yibin Kang et al.
CANCER CELL (2013)
SDH Mutations Establish a Hypermethylator Phenotype in Paraganglioma
Eric Letouze et al.
CANCER CELL (2013)
Hexokinase II in breast carcinoma: A potent prognostic factor associated with hypoxia-inducible factor-1α and Ki-67
Akiko Sato-Tadano et al.
CANCER SCIENCE (2013)
Prospective evaluation of serum sarcosine and risk of prostate cancer in the Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial
Stella Koutros et al.
CARCINOGENESIS (2013)
Mechanisms Governing Metastatic Dormancy and Reactivation
Filippo G. Giancotti
CELL (2013)
T cell anergy, exhaustion, senescence, and stemness in the tumor microenvironment
Joel Crespo et al.
CURRENT OPINION IN IMMUNOLOGY (2013)
Mitochondrial complex I activity and NAD+/NADH balance regulate breast cancer progression
Antonio F. Santidrian et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Understanding Metabolic Regulation and Its Influence on Cell Physiology
Christian M. Metallo et al.
MOLECULAR CELL (2013)
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
Jaekyoung Son et al.
NATURE (2013)
Identification of a population of blood circulating tumor cells from breast cancer patients that initiates metastasis in a xenograft assay
Irene Baccelli et al.
NATURE BIOTECHNOLOGY (2013)
Roadblocks to translational advances on metastasis research
Thomas Brabletz et al.
NATURE MEDICINE (2013)
Role of Glutathione in Cancer Progression and Chemoresistance
Nicola Traverso et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells
Thomas Green et al.
PROSTATE (2013)
Metabolomic signatures of aggressive prostate cancer
Jonathan E. McDunn et al.
PROSTATE (2013)
Evaluating cell lines as tumour models by comparison of genomic profiles
Silvia Domcke et al.
NATURE COMMUNICATIONS (2013)
L-Proline Induces a Mesenchymal-like Invasive Program in Embryonic Stem Cells by Remodeling H3K9 and H3K36 Methylation
Stefania Comes et al.
STEM CELL REPORTS (2013)
The Role of Sarcosine Metabolism in Prostate Cancer Progression
Amjad P. Khan et al.
NEOPLASIA (2013)
Activated lymphocytes as a metabolic model for carcinogenesis
Andrew N. Macintyre et al.
CANCER & METABOLISM (2013)
Pyruvate uptake is increased in highly invasive ovarian cancer cells under anoikis conditions for anaplerosis, mitochondrial function, and migration
Christine A. Caneba et al.
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2012)
Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components
Masato Ogura et al.
BIOCHEMICAL JOURNAL (2012)
Mutations in isocitrate dehydrogenase 2 accelerate glioma cell migration via matrix metalloproteinase-2 and 9
Yuejun Fu et al.
BIOTECHNOLOGY LETTERS (2012)
Cancer stem cells and EMT in carcinoma
Adrian Biddle et al.
CANCER AND METASTASIS REVIEWS (2012)
Proline Oxidase Promotes Tumor Cell Survival in Hypoxic Tumor Microenvironments
Wei Liu et al.
CANCER RESEARCH (2012)
Impaired Insulin/IGF1 Signaling Extends Life Span by Promoting Mitochondrial L-Proline Catabolism to Induce a Transient ROS Signal
Kim Zarse et al.
CELL METABOLISM (2012)
IDH1 and IDH2 Mutations in Tumorigenesis: Mechanistic Insights and Clinical Perspectives
Hui Yang et al.
CLINICAL CANCER RESEARCH (2012)
Indoleamine 2,3-dioxygenase, a new prognostic marker in sentinel lymph nodes of melanoma patients
Reinhart Speeckaert et al.
EUROPEAN JOURNAL OF CANCER (2012)
Pyruvate kinase type M2 is upregulated in colorectal cancer and promotes proliferation and migration of colon cancer cells
Cheng-Fu Zhou et al.
IUBMB LIFE (2012)
Isocitrate Dehydrogenase (IDH) Mutations Promote a Reversible ZEB1/MicroRNA (miR)-200-dependent Epithelial-Mesenchymal Transition (EMT)
Alexandra R. Grassian et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
De novo sequencing of circulating miRNAs identifies novel markers predicting clinical outcome of locally advanced breast cancer
Xiwei Wu et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2012)
Glucose Oxidation Modulates Anoikis and Tumor Metastasis
Sushama Kamarajugadda et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Physiological Roles of Mitochondrial Reactive Oxygen Species
Laura A. Sena et al.
MOLECULAR CELL (2012)
Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production
P. S. Ward et al.
ONCOGENE (2012)
Differential Expression of Metabolic Genes in Tumor and Stromal Components of Primary and Metastatic Loci in Pancreatic Adenocarcinoma
Nina V. Chaika et al.
PLOS ONE (2012)
Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC
Wei Liu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Serum sarcosine increases the accuracy of prostate cancer detection in patients with total serum PSA less than 4.0?ng/ml
Giuseppe Lucarelli et al.
PROSTATE (2012)
Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
Mohit Jain et al.
SCIENCE (2012)
Signaling in Control of Cell Growth and Metabolism
Patrick S. Ward et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
Fully automated solid-phase microextraction-fast gas chromatography-mass spectrometry method using a new ionic liquid column for high-throughput analysis of sarcosine and N-ethylglycine in human urine and urinary sediments
F. Bianchi et al.
ANALYTICA CHIMICA ACTA (2011)
GC/MS-based metabolomic approach to validate the role of urinary sarcosine and target biomarkers for human prostate cancer by microwave-assisted derivatization
Hao Wu et al.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY (2011)
High-Throughput Selection, Enumeration, Electrokinetic Manipulation, and Molecular Profiling of Low-Abundance Circulating Tumor Cells Using a Microfluidic System
Udara Dharmasiri et al.
ANALYTICAL CHEMISTRY (2011)
Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
Sophia Y. Lunt et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, VOL 27 (2011)
Enhanced serine production by bone metastatic breast cancer cells stimulates osteoclastogenesis
Sirkku Pollari et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
Proinvasion Metastasis Drivers in Early-Stage Melanoma Are Oncogenes
Kenneth L. Scott et al.
CANCER CELL (2011)
Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases
Wei Xu et al.
CANCER CELL (2011)
Dissecting the Oncogenic and Tumorigenic Potential of Differentiated Human Induced Pluripotent Stem Cells and Human Embryonic Stem Cells
Zhumur Ghosh et al.
CANCER RESEARCH (2011)
Phosphoglucose Isomerase/Autocrine Motility Factor Mediates Epithelial-Mesenchymal Transition Regulated by miR-200 in Breast Cancer Cells
Aamir Ahmad et al.
CANCER RESEARCH (2011)
Reduction of metastasis using a non-volatile buffer
Arig Ibrahim Hashim et al.
CLINICAL & EXPERIMENTAL METASTASIS (2011)
Migration of MDA-MB-231 breast cancer cells depends on the availability of exogenous lipids and cholesterol esterification
Caryl J. Antalis et al.
CLINICAL & EXPERIMENTAL METASTASIS (2011)
HIF-1α stabilization by mitochondrial ROS promotes Met-dependent invasive growth and vasculogenic mimicry in melanoma cells
Giuseppina Comito et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
Is sarcosine a biomarker for prostate cancer?
Haleem J. Issaq et al.
JOURNAL OF SEPARATION SCIENCE (2011)
Sarcosine in Prostate Cancer Tissue is Not a Differential Metabolite for Prostate Cancer Aggressiveness and Biochemical Progression
Florian Jentzmik et al.
JOURNAL OF UROLOGY (2011)
The important role of glycine N-methyltransferase in the carcinogenesis and progression of prostate cancer
Yoo Hyun Song et al.
MODERN PATHOLOGY (2011)
Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis
Jason W. Locasale et al.
NATURE GENETICS (2011)
Serum Methionine Metabolites Are Risk Factors for Metastatic Prostate Cancer Progression
Sally Stabler et al.
PLOS ONE (2011)
Metabolomic Profiling Reveals a Role for Androgen in Activating Amino Acid Metabolism and Methylation in Prostate Cancer Cells
Nagireddy Putluri et al.
PLOS ONE (2011)
Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations
Katherine A. Janeway et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Two ubiquitin ligases, APC/C-Cdh1 and SKP1-CUL1-F (SCF)-β-TrCP, sequentially regulate glycolysis during the cell cycle
Slavica Tudzarova et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance
Jean-Pierre Gillet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
A Multiplex Model of Combining Gene-Based, Protein-Based, and Metabolite-Based With Positive and Negative Markers in Urine for the Early Diagnosis of Prostate Cancer
Da-Long Cao et al.
PROSTATE (2011)
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
Dimitrios Anastasiou et al.
SCIENCE (2011)
Otto Warburg's contributions to current concepts of cancer metabolism
Willem H. Koppenol et al.
NATURE REVIEWS CANCER (2011)
Regulation of cancer cell metabolism
Rob A. Cairns et al.
NATURE REVIEWS CANCER (2011)
Discriminating Isogenic Cancer Cells and Identifying Altered Unsaturated Fatty Acid Content as Associated with Metastasis Status, Using K-Means Clustering and Partial Least Squares-Discriminant Analysis of Raman Maps
Martin Hedegaard et al.
ANALYTICAL CHEMISTRY (2010)
ROS-mediated mechanisms of autophagy stimulation and their relevance in cancer therapy
Michael Dewaele et al.
AUTOPHAGY (2010)
Fish oil prevents breast cancer cell metastasis to bone
Chandi Charan Mandal et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Targeting Mitochondrial Glutaminase Activity Inhibits Oncogenic Transformation
Jian-Bin Wang et al.
CANCER CELL (2010)
Indoleamine 2,3-Dioxygenase Is It an Immune Suppressor?
Hatem Soliman et al.
CANCER JOURNAL (2010)
Myeloid-Derived Suppressor Cells Inhibit T-Cell Activation by Depleting Cystine and Cysteine
Minu K. Srivastava et al.
CANCER RESEARCH (2010)
Ketones and lactate fuel tumor growth and metastasis Evidence that epithelial cancer cells use oxidative mitochondrial metabolism
Gloria Bonuccelli et al.
CELL CYCLE (2010)
HIF-1: upstream and downstream of cancer metabolism
Gregg L. Semenza
CURRENT OPINION IN GENETICS & DEVELOPMENT (2010)
Re: Florian Jentzmik, Carsten Stephan, Kurt Miller, et al. Sarcosine in Urine After Digital Rectal Examination Fails as a Marker in Prostate Cancer Detection and Identification of Aggressive Tumours. Eur Urol 2010;58:12-8
Amitha K. Hewavitharana
EUROPEAN UROLOGY (2010)
Fatty acid synthase as a potential therapeutic target in cancer
Richard Flavin et al.
FUTURE ONCOLOGY (2010)
Metabolism strikes back: metabolic flux regulates cell signaling
Christian M. Metallo et al.
GENES & DEVELOPMENT (2010)
An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
Joshua D. Mezrich et al.
JOURNAL OF IMMUNOLOGY (2010)
IDO Upregulates Regulatory T Cells via Tryptophan Catabolite and Suppresses Encephalitogenic T Cell Responses in Experimental Autoimmune Encephalomyelitis
Yaping Yan et al.
JOURNAL OF IMMUNOLOGY (2010)
Indoleamine 2,3-Dioxygenase(+) Cells Correspond to the BDCA2(+) Plasmacytoid Dendritic Cells in Human Melanoma Sentinel Nodes
Gianni Gerlini et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2010)
Tumour seeding in a case of malignant melanoma due to fine needle aspiration of a lymph node
A. J. Robinson et al.
JOURNAL OF PLASTIC RECONSTRUCTIVE AND AESTHETIC SURGERY (2010)
Cellular Metabolic Stress: Considering How Cells Respond to Nutrient Excess
Kathryn E. Wellen et al.
MOLECULAR CELL (2010)
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer
A. Singh et al.
ONCOGENE (2010)
Docosahexaenoic Acid Induces Apoptosis in MCF-7 Cells In Vitro and In Vivo via Reactive Oxygen Species Formation and Caspase 8 Activation
Ki Sung Kang et al.
PLOS ONE (2010)
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
Frank Weinberg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Evidence for an Alternative Glycolytic Pathway in Rapidly Proliferating Cells
Matthew G. Vander Heiden et al.
SCIENCE (2010)
Simultaneous Foxp3 and IDO expression is associated with sentinel lymph node metastases in breast cancer
Aaron S. Mansfield et al.
BMC CANCER (2009)
Bicarbonate Increases Tumor pH and Inhibits Spontaneous Metastases
Ian F. Robey et al.
CANCER RESEARCH (2009)
Gene expression profiles and breast cancer metastasis: a genetic perspective
Kent W. Hunter et al.
CLINICAL & EXPERIMENTAL METASTASIS (2009)
Upregulation of glycolytic enzymes in proteins secreted from human colon cancer cells with 5-fluorouracil resistance
Young-Kyoung Shin et al.
ELECTROPHORESIS (2009)
Transketolase-like protein 1 (TKTL1) is required for rapid cell growth and full viability of human tumor cells
Xiaojun Xu et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Phosphoglucose isomerase enhances colorectal cancer metastasis
Soichi Tsutsumi et al.
INTERNATIONAL JOURNAL OF ONCOLOGY (2009)
IDO Mediates TLR9-Driven Protection from Experimental Autoimmune Diabetes
Francesca Fallarino et al.
JOURNAL OF IMMUNOLOGY (2009)
Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment
Zachary T. Schafer et al.
NATURE (2009)
Cancer-associated IDH1 mutations produce 2-hydroxyglutarate
Lenny Dang et al.
NATURE (2009)
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
Arun Sreekumar et al.
NATURE (2009)
Lactate promotes glioma migration by TGF-β2-dependent regulation of matrix metalloproteinase-2
Fusun Baumann et al.
NEURO-ONCOLOGY (2009)
Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome
Elaine R. Mardis et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
IDH1 and IDH2 Mutations in Gliomas
Hai Yan et al.
NEW ENGLAND JOURNAL OF MEDICINE (2009)
A Distinct Macrophage Population Mediates Metastatic Breast Cancer Cell Extravasation, Establishment and Growth
Binzhi Qian et al.
PLOS ONE (2009)
miR-200 Enhances Mouse Breast Cancer Cell Colonization to Form Distant Metastases
Derek M. Dykxhoorn et al.
PLOS ONE (2009)
Metastasis: from dissemination to organ-specific colonization
Don X. Nguyen et al.
NATURE REVIEWS CANCER (2009)
Expression patterns in mouse embryos of neuroleukin/glucose-6-phosphate isomerase and autocrine motility factor receptor
A. Repiso et al.
ANATOMIA HISTOLOGIA EMBRYOLOGIA (2008)
Increased expression of transketolase-like-1 in papillary thyroid carcinomas smaller than 1.5 cm in diameter is associated with lymph-node metastases
Monica Zerilli et al.
CANCER (2008)
Epithelial-Mesenchymal Transition Induced by Growth Suppressor p12CDK2-AP1 Promotes Tumor Cell Local Invasion but Suppresses Distant Colony Growth
Takanori Tsuji et al.
CANCER RESEARCH (2008)
The epithelial-mesenchymal transition generates cells with properties of stem cells
Sendurai A. Mani et al.
CELL (2008)
Redox regulation of anoikis: reactive oxygen species as essential mediators of cell survival
E. Giannoni et al.
CELL DEATH AND DIFFERENTIATION (2008)
Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells
Candace M. Cham et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Metastasis is promoted by a bioenergetic switch: New targets for progressive renal cell cancer
Sigrun Langbein et al.
INTERNATIONAL JOURNAL OF CANCER (2008)
Expanding chemical biology of 2-oxoglutarate oxygenases
Christoph Loenarz et al.
NATURE CHEMICAL BIOLOGY (2008)
An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors
Ittai Ben-Porath et al.
NATURE GENETICS (2008)
ROS-generating mitochondrial DNA mutations can regulate tumor cell metastasis
Kaori Ishikawa et al.
SCIENCE (2008)
Metastasis: a therapeutic target for cancer
Patricia S. Steeg et al.
NATURE CLINICAL PRACTICE ONCOLOGY (2008)
Central carbon metabolism in the progression of mammary carcinoma
Adam D. Richardson et al.
BREAST CANCER RESEARCH AND TREATMENT (2008)
Antitumor activities of TEMS-Fc: An engineered antibody-like molecule targeting tumor endothelial marker 8
Hai-Feng Duan et al.
JOURNAL OF THE NATIONAL CANCER INSTITUTE (2007)
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer
Srinivas Nagaraj et al.
NATURE MEDICINE (2007)
Tumor microenvironment abnormalities: Causes, consequences, and strategies to normalize
Dai Fukumura et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2007)
Impact of mutant p53 functional properties on TP53 mutation patterns and tumor phenotype:: Lessons from recent developments in the IARC TP53 database
Audrey Petitjean et al.
HUMAN MUTATION (2007)
Specific amino acid dependency regulates the cellular behavior of melanoma
Ya-Min Fu et al.
JOURNAL OF NUTRITION (2007)
The ERK1/2 mitogen-activated protein kinase pathway as a master regulator of the G1- to S-phase transition
S. Meloche et al.
ONCOGENE (2007)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
Karin Fischer et al.
BLOOD (2007)
L-arginine availability regulates T-lymphocyte cell-cycle progression
Paulo C. Rodriguez et al.
BLOOD (2007)
Adaptation of energy metabolism in breast cancer brain metastases
Emily I. Chen et al.
CANCER RESEARCH (2007)
Transketolase-like 1 expression correlates with subtypes of ovarian cancer and the presence of distant metastases
M. Krockenberger et al.
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER (2007)
Pathway-specific differences between tumor cell lines and normal and tumor tissue cells
Adam Ertel et al.
MOLECULAR CANCER (2006)
Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: the role of ROS/superoxides, NFAT and MEK/ERK signaling
Y. Liu et al.
ONCOGENE (2006)
Succinate dehydrogenase and fumarate hydratase:: linking mitochondrial dysfunction and cancer
A. King et al.
ONCOGENE (2006)
PFKFB3 gene silencing decreases glycolysis, induces cell-cycle delay and inhibits anchorage-independent growth in HeLa cells
M. N. Calvo et al.
FEBS LETTERS (2006)
An osteopontin splice variant induces anchorage independence in human breast cancer cells
B He et al.
ONCOGENE (2006)
Expression of transketolase TKTL1 predicts colon and urothelial cancer patient survival: Warburg effect reinterpreted
S Langbein et al.
BRITISH JOURNAL OF CANCER (2006)
Hexosamines, insulin resistance, and the complications of diabetes: current status
MG Buse
AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM (2006)
Metastasis: a question of life or death
P Mehlen et al.
NATURE REVIEWS CANCER (2006)
Genes that mediate breast cancer metastasis to lung
AJ Minn et al.
NATURE (2005)
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
JK Brunelle et al.
CELL METABOLISM (2005)
Breast cancer metastasis to bone: Mechanisms of osteolysis and implications for therapy
W Kozlow et al.
JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA (2005)
Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase
MA Selak et al.
CANCER CELL (2005)
Antigen-specific inhibition of CD8+ T cell response by immature myeloid cells in cancer is mediated by reactive oxygen species
S Kusmartsev et al.
JOURNAL OF IMMUNOLOGY (2004)
Tumour cell growth in culture: dependence on arginine
G Caso et al.
CLINICAL SCIENCE (2004)
Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses
PC Rodriguez et al.
CANCER RESEARCH (2004)
Lactate in solid malignant tumors: Potential basis of a metabolic classification in clinical oncology
S Walenta et al.
CURRENT MEDICINAL CHEMISTRY (2004)
Genes of glycolysis are ubiquitously overexpressed in 24 cancer classes
B Altenberg et al.
GENOMICS (2004)
Inhibition of MHC II gene transcription by nitric oxide and antioxidants
O Harari et al.
CURRENT PHARMACEUTICAL DESIGN (2004)
Tumor type M2 pyruvate kinase expression in gastric cancer, colorectal cancer and controls
Bo Zhang et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2004)
Why do cancers have high aerobic glycolysis?
RA Gatenby et al.
NATURE REVIEWS CANCER (2004)
The role of glutathione-S-transferase in anti-cancer drug resistance
DM Townsend et al.
ONCOGENE (2003)
Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase
C Uyttenhove et al.
NATURE MEDICINE (2003)
Glucose-6-phosphate isomerase is necessary for embryo implantation in the domestic ferret
LC Schulz et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Metabolic classification of human rectal adenocarcinomas: a novel guideline for clinical oncologists?
S Walenta et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2003)
The enzymatic activity of phosphoglucose isomerase is not required for its cytokine function
S Tsutsumi et al.
FEBS LETTERS (2003)
A molecular signature of metastasis in primary solid tumors
S Ramaswamy et al.
NATURE GENETICS (2003)
Adoptive T cell therapy using antigen-specific CD8+ T cell clones for the treatment of patients with metastatic melanoma:: In vivo persistence, migration, and antitumor effect of transferred T cells
C Yee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Glutathione regulates the expression of γ-glutamylcysteine synthetase via the Met4 transcription factor
GL Wheeler et al.
MOLECULAR MICROBIOLOGY (2002)
Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction
L Rivoltini et al.
IMMUNOLOGICAL REVIEWS (2002)
Inhibition of allogeneic T cell proliferation by indoleamine 2,3-dioxygenase-expressing dendritic cells:: Mediation of suppression by tryptophan metabolites
P Terness et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2002)
Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
DM Brizel et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2001)
Autocrine motility factor enhances hepatoma cell invasion across the basement membrane through activation of β1 integrins
T Torimura et al.
HEPATOLOGY (2001)
Sustained nitric oxide production in macrophages requires the arginine transporter CAT2
B Nicholson et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1α degradation
E Berra et al.
FEBS LETTERS (2001)