Journal
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 56, Issue 36, Pages 10920-10923Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.201706325
Keywords
alkynes; C-H activation; palladium; regioselectivity; spiro compounds
Categories
Funding
- University of Toronto
- Alphora Research, Inc.
- Natural Sciences and Engineering Research Council (NSERC)
- Ontario Graduate Scholarship program
Ask authors/readers for more resources
A Pd-catalyzed spirocyclization involving a sequential carbopalladation, intramolecular C-H activation, and a highly regioselective alkyne insertion to afford spirooxindoles and spirodihydrobenzofurans has been achieved. The spirocyclic products were generated in good to excellent yields with complete regiocontrol in a readily scalable procedure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available
Share Paper
