Journal
JOURNAL OF VISCERAL SURGERY
Volume 154, Issue 6, Pages 421-429Publisher
ELSEVIER MASSON, CORP OFF
DOI: 10.1016/j.jviscsurg.2017.06.011
Keywords
Splenectomy; Hematology; Splenomegaly; Hypersplenism; Hemolysis; Myeloproliferative syndrome; Lymphoproliferative syndrome
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Splenectomy is part of the therapeutic arsenal for benign or malignant hematological disorders that constitute the main indication for elective splenectomy. With the development of minimally invasive approaches, and in particular, laparoscopy, as well as the advent of monoclonal antibody therapy, the indications and the outcomes of splenectomy for hematologic disease have changed in recent years. Nonetheless, splenectomy has its place in hemoglobinopathies and hemolytic diseases, improves thrombocytopenia in refractory immune thrombocytopenic purpura, can reverse sequelae linked to voluminous splenomegaly secondary to myelofibrosis, or can be used for diagnostic purposes or for splenomegaly in lymphoproliferative syndromes. (C) 2017 Elsevier Masson SAS. All rights reserved.
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