Journal
GLOBAL HEART
Volume 12, Issue 3, Pages 199-+Publisher
UBIQUITY PRESS LTD
DOI: 10.1016/j.gheart.2016.03.639
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Funding
- National Institute for Health Research (NIHR) CLAHRC (Collaboration for Leadership in Applied Health Research and Care) West Midlands initiative
- U.K. Department for International Development
- NIHR Cochrane Programme grant
- National Institute for Health Research [10/4001/13] Funding Source: researchfish
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This study sought to determine the effectiveness of multiple risk factor interventions aimed at modifying major cardiovascular risk factors for the primary prevention of cardiovascular disease in low-and middle-income countries (LMIC). We searched electronic databases for randomized controlled trials of health promotion interventions to achieve behavior change. The pooled effect indicated a reduction in systolic blood pressure (-6.72 mm Hg; 95% confidence interval [CI]: -9.82 to -3.61; I-2 = 91%), diastolic blood pressure (-4.40 mm Hg; 95% CI: -6.47 to -2.34; I-2 = 92%), body mass index (-0.76 kg/m(2); 95% CI: -1.29 to -0.22; I-2 = 80%), and waist circumference (-3.31 cm; 95% CI: -4.77 to -1.86; I-2 = 55%) in favor of multiple risk factor interventions. There is some evidence that multiple risk factor interventions may lower blood pressure levels and anthropometrics in populations in LMIC settings at high risk of hypertension and diabetes.
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