Journal
MEDCHEMCOMM
Volume 8, Issue 5, Pages 871-885Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7md00097a
Keywords
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Funding
- School of Graduate Studies and Research, American University of Ras Al Khaimah [AAS/003/15]
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Cancer is one of the major causes of worldwide human mortality. A wide range of cytotoxic drugs are available on the market, and several compounds are in different phases of clinical trials. Many studies suggest that these cytotoxic molecules are also associated with different types of adverse side effects; therefore researchers around the globe are involved in the development of more efficient and safer anticancer drugs. In recent years, quinazoline and its derivatives have been considered as a novel class of cancer chemotherapeutic agents that show promising activity against different tumors. The aim of this article is to comprehensively review and highlight the recent developments concerning the anticancer activity of quinazoline derivatives as well as offer perspectives on the development of novel quinazoline derivatives as anticancer agents in the near future.
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