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Post-translational regulation of plant immunity

Journal

CURRENT OPINION IN PLANT BIOLOGY
Volume 38, Issue -, Pages 124-132

Publisher

CURRENT BIOLOGY LTD
DOI: 10.1016/j.pbi.2017.05.004

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Funding

  1. National Institutes of Health [2R01-GM069594-09]
  2. Howard Hughes Medical Institute-Gordon
  3. Duke University Hargitt Fellowship
  4. Betty Moore Foundation [GBMF3032]

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Plants have evolved multi-layered molecular defense strategies to protect against pathogens. Plant immune signaling largely relies on post-translational modifications (PTMs) to induce rapid alterations of signaling pathways to achieve a response that is appropriate to the type of pathogen and infection pressure. In host cells, dynamic PTMs have emerged as powerful regulatory mechanisms that cells use to adjust their immune response. PTM is also a virulence strategy used by pathogens to subvert host immunity through the activities of effector proteins secreted into the host cell. Recent studies focusing on deciphering post-translational mechanisms underlying plant immunity have offered an in-depth view of how PTMs facilitate efficient immune responses and have provided a more dynamic and holistic view of plant immunity.

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