Journal
CHEMICAL SCIENCE
Volume 8, Issue 8, Pages 5240-5247Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/c7sc01968h
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Funding
- University of Manchester
- SCI
- EPSRC
- Engineering and Physical Sciences Research Council [1653669] Funding Source: researchfish
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The direct functionalisation of allenes under copper catalysis enables efficient access to enantioenriched, densely functionalised molecules. In this review we explore the breadth and depth of a versatile reaction manifold, which involves the element-cupration of allenes to generate allyl copper intermediates that are subsequently coupled with diverse arrays of electrophiles.
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