Mussel-inspired nano-multilayered coating on magnesium alloys for enhanced corrosion resistance and antibacterial property

Magnesium alloys are promising candidates for load-bearing orthopedic implants due to their biodegradability and mechanical resemblance to natural bone tissue. However, the high degradation rate and the risk of implant-associated infections pose grand challenges for their clinical applications. Herein, we developed a nano-multilayered coating strategy through polydopamine and chitosan assisted layer-by layer assembly of osteoinductive carbonated apatite and antibacterial sliver nanoparticles on the surface of AZ31 magnesium alloys. The fabricated nano-multilayered coating can not only obviously enhance the corrosion resistance but also significantly increase the antibacterial activity and demonstrate better biocompatility of magnesium alloys. (C) 2017 Elsevier B.V. All rights reserved.