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Dendrimers for ocular drug delivery

Journal

CANADIAN JOURNAL OF CHEMISTRY
Volume 95, Issue 9, Pages 897-902

Publisher

CANADIAN SCIENCE PUBLISHING
DOI: 10.1139/cjc-2017-0193

Keywords

dendrimer; ocular drug delivery; nanomedicine

Funding

  1. National Institutes of Health [R01EY024072]

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Existing methods of administering ocular drugs are limited in either their safety or efficiency. Nanomedicine therapies have the potential to address this deficiency by creating vehicles that can control drug biodistribution. Dendrimers are synthetic polymeric nanoparticles with a unique, highly organized branching structure. In recent years, promising results using dendrimer vehicles to deliver ocular drugs through different routes of administration have been reported. In this minireview, we briefly summarize these results with emphasis on the dendrimer modifications used to target different ocular structures.

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