Journal
ANNUAL REVIEW OF CHEMICAL AND BIOMOLECULAR ENGINEERING, VOL 8
Volume 8, Issue -, Pages 249-283Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev-chembioeng-080615-033546
Keywords
process synthesis; mathematical programming; superstructures; process flowsheets; conceptual design; reactor networks; distillation sequences; heat exchanger networks
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This article first reviews recent developments in process synthesis and discusses some of the major challenges in the theory and practice in this area. Next, the article reviews key concepts in optimization-based conceptual design, namely superstructure representations, multilevel models, optimization methods, and modeling environments. A brief review of the synthesis of major subsystems and flowsheets is presented. Finally, the article closes with a critical assessment and future research challenges for the process synthesis area.
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