4.7 Article

Nickel-catalyzed methylation of aryl halides/tosylates with methyl tosylate

Journal

CHEMICAL COMMUNICATIONS
Volume 53, Issue 73, Pages 10180-10183

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/c7cc06106d

Keywords

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Funding

  1. Chinese NSF [21372151, 21572127]
  2. Shanghai Municipal Education Commission for the Peak Discipline Construction [13-A302-15-L02]

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This work describes the cross-electrophile methylation of aryl bromides and aryl tosylates with methyl tosylate. The mild reaction conditions allow effective methylation of a wide set of heteroaryl electrophiles and dimethylation of dibromoarenes.

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